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Compound In Green Tea Could Kill Drug-Resistant Bacteria

Compound in green tea could kill drug-resistant bacteria. A recent study found that a green tea compound might boost existing drugs.

Antibiotic-resistant bacteria are becoming a major threat to global health. According to the Centers for Disease Control and Resistance (CDC). Each year in the United States alone, at least 2 million people get affected by drug-resistant bacteria, leading to about 23,000 deaths.

In a recent study, the researchers investigated the green tea compound known as epigallocatechin (EGCG). They focused on the bacterium Pseudomonas aeruginosa.

These bacteria are growing resistant to many drugs and can cause severe infections to the skin, the respiratory, the blood, and urinary tracts. Current treatment only involves a combination of antibiotics.

The research findings are published in the Journal of Medical Microbiology.

In the research, the investigators combined EGCG with aztreonam, an antibiotic used to treat P. aeruginosa.  They used an animal model for their investigation.

They found that the combination of EGCG and aztreonam showed more effective results than the drug or EGCG alone. EGCG allows antibiotics to pass through more easily, according to scientists.

“Antimicrobial resistance (AMR) is a serious threat to global public health. Without effective antibiotics, the success of medical treatments will be compromised. We urgently need to develop novel antibiotics in the fight against AMR,” lead author Dr. Jonathan Betts said.

“Natural products, such as EGCG, used in combination with currently licensed antibiotics, may be a way of improving their effectiveness and clinically useful lifespan,” Dr. Betts added.

 

 

 

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